Helix
2nd Place • YHackAI-native genomic IDE for analyzing, ranking, editing, and comparing DNA sequences with live structure feedback.
Paste a DNA sequence or design goal and Helix walks it through annotation, candidate generation, ranking, mutation editing, copilot guidance, and 3D structure visualization.
My role: Built much of the backend pipeline and copilot flow in FastAPI, including orchestration, API contracts, Evo 2 and structure integrations, and test coverage.
From design prompt to editable genomic candidates with live structure feedback.
What I built:
- Built around an 8-stage genomic analysis flow: sequence intake, annotation, Evo 2 scoring, candidate generation, ranking, editing, compare, and explanation.
- Shipped backend orchestration, session handling, and tests so the genomic workspace could stream progress and stay stable across retries.
- Connected product surfaces for Explorer, Design Studio, Compare, Copilot, and 3D structure views so edits and scores stayed in one workflow.
- Grounded the workspace with retrieval and domain context from sources like NCBI, PubMed, and ClinVar while keeping the product usable for non-experts.
